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The effect of candesartan ester and function |
source:Vitalpharms Company Ltd. Release date:2017/12/6 13:09:24 |
Candesartan ester piece mainly of candesartan ester, chemical name: (+) - 1 - [[(cyclohexanol oxygen generation) carbonyl] oxygen generation] ethyl - 2 - ethoxy - 1 - [(2 '- (1 h - four nitrogen imidazolyl - 5) - [1, 1' - al phenyl] - 4 - base] methyl] - 1 h - benzene and imidazole - 7 - carboxylic acid ester. Candesartan ester is a new generation of Ang Ⅱ receptor blocker, candesartan ester effect mainly treatment of essential hypertension. The role of candesartan ester piece: candesartan ester in the body quickly is hydrolyzed into active metabolite candesartan. Candesartan for angiotensin II AT1 receptor antagonist, by combined with vascular smooth muscle of AT1 receptor antagonist of angiotensin II vasoconstriction, reducing peripheral vascular resistance. Another thought: candesartan can inhibit the adrenal glands secrete aldosterone and play a certain antihypertensive effect. Candesartan acetate tablets, the average adult 1, 1, 1 times 4 to 8 mg, can increase the dose of 12 mg when necessary. Candesartan ester used in the treatment of essential hypertension, can be used alone, can also be used with other antihypertensive drug combination, achieved good effect. Patient friend taking candesartan ester were taboo should pay attention to the following: (1) on candesartan ester compounds have allergy history of patients. (2) nursing mothers avoid drugs, must take medicine, should stop breastfeeding. (3) the patients with severe liver and renal insufficiency or bile clogged. Looked at the above introduction, believe everybody already knows the effect of candesartan ester and function, if there is not understand place, can consult candesartan ester manufacturer of professional and technical personnel, must be able to solve your problem. Hope these information can help to you.
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